Primary Ciliary Dyskinesia DNAI2

Primary Ciliary Dyskinesia [DNAI2]: Mutations in DNAI2 cause abnormal cilia formation leading to respiratory problems such as chronic infection (due to improper clearing of the lungs), infertility in males (due to abnormal sperm tails), and possible situs invertus (organs forming on the opposite side of the body).

Ashkenazi Jewish Carrier Frequency: 1 in 200