Beta-Globin-Related Hemoglobinopathies

Beta-globin-related Hemoglobinopathies [HBB]: A group of disorders involving the quantity and/or quality of the beta-globin protein. Deficient or abnormal beta-globin results in a deficiency in hemoglobin which leads to abnormalities of the red blood cells’ ability to properly transfer oxygen throughout the body. Affected individuals are at risk for poor growth, organ damage (generalized, or specified to the spleen), episodes of pain, and anemia.

Sephardic-Mizrahi Jewish Carrier Frequency: N/A